Ro 60-0175 fumarate ( Ro 600175 fumarate )

产品货号. M12588 CAS No. 169675-09-6

Ro 60-0175 is a potent, selective 5-HT2C receptor agonist.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
5MG	￥3021	有现货
50MG	￥11664	有现货
100MG	￥17658	有现货
200MG	获取报价	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

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生物学信息

产品名称

Ro 60-0175 fumarate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Ro 60-0175 is a potent, selective 5-HT2C receptor agonist.
产品描述

Ro 60-0175 is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively; induces hypolocomotion in rats at doses greater than 0.5 mg/kg s.c.; (0.3 and 1 mg/kg s.c.) simultaneously reduces both unpunished and punished lever pressing, a profile consistent with sedation, induces sedative-like responses via 5-HT(2C) receptor activation in vivo.
同义词

Ro 600175 fumarate
通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

5-HT Receptor
研究领域

Neurological Disease
适应症

——

化学信息

CAS Number

169675-09-6
分子量

342.75
分子式

C15H16ClFN2O4
纯度

>98% (HPLC)
溶解度

——
SMILES

C[C@@H](CN1C=CC2=CC(=C(C=C21)Cl)F)N.C(=C/C(=O)O)\C(=O)O
化学全称

(S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine fumarate

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Damjanoska KJ, et al. J Pharmacol Exp Ther. 2003 Mar;304(3):1209-16.
2. Vickers SP, et al. Br J Pharmacol. 2000 Jul;130(6):1305-14.
3. Kennett G, et al. Eur J Pharmacol. 2000 Jan 10;387(2):197-204.
4. Jenck F, et al. Eur Neuropsychopharmacol. 1998 Aug;8(3):161-8.

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产品手册

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